519 research outputs found

    A strong convergence theorem on solving common solutions for generalized equilibrium problems and fixed-point problems in Banach space

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    Abstract In this paper, the common solution problem (P1) of generalized equilibrium problems for a system of inverse-strongly monotone mappings and a system of bifunctions satisfying certain conditions, and the common fixed-point problem (P2) for a family of uniformly quasi-&#981;-asymptotically nonexpansive and locally uniformly Lipschitz continuous or uniformly H&#246;lder continuous mappings are proposed. A new iterative sequence is constructed by using the generalized projection and hybrid method, and a strong convergence theorem is proved on approximating a common solution of (P1) and (P2) in Banach space. 2000 MSC: 26B25, 40A05</p

    Approximations for Equilibrium Problems and Nonexpansive Semigroups

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    We introduce a new iterative method for finding a common element of the set of solutions of an equilibrium problem and the set of all common fixed points of a nonexpansive semigroup and prove the strong convergence theorem in Hilbert spaces. Our result extends the recent result of Zegeye and Shahzad (2013). In the last part of the paper, by the way, we point out that there is a slight flaw in the proof of the main result in Shehu's paper (2012) and perfect the proof

    Shrinking Projection Methods for Split Common Fixed-Point Problems in Hilbert Spaces

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    Inspired by Moudafi (2011) and Takahashi et al. (2008), we present the shrinking projection method for the split common fixed-point problem in Hilbert spaces, and we obtain the strong convergence theorem. As a special case, the split feasibility problem is also considered

    Iterative Methods for Equilibrium Problems and Monotone Inclusion Problems in Hilbert Spaces

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    We introduce a new iterative method for finding a common element of the set of solutions of an equilibrium problem and the set of zeros of the sum of maximal monotone operators, and we obtain strong convergence theorems in Hilbert spaces. We also apply our results to the variational inequality and convex minimization problems. Our results extend and improve the recent result of Takahashi et al. (2012)

    Tracking the intracellular drug release from graphene oxide using surface-enhanced Raman spectroscopy

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    NSFC [21073224, 51361130033]; MOST [2013CB933703]; Innovation Project of CAS [KJCX2.YW.M12]; State Key Laboratory of Physical Chemistry of Solid Surfaces at Xiamen UniversityWe have developed a graphene oxide (GO)-based nanoplatform simultaneously loaded with a chemical drug and Ag nanoparticles (NPs), and employed it to study the drug release from GO in living cells by surface-enhanced Raman spectroscopy (SERS). In our strategy, doxorubicin (DOX), a typical model anticancer drug, was loaded onto chemically prepared GO by means of pi-pi stacking, while the Ag NPs were covalently modified onto GO. After incubation of the DOX- and Ag NPs-loaded GO with Ca Ski cells for several hours, DOX will detach from the GO in an acidic environment due to the pH-dependent p-p interaction between DOX and GO. Real-time measurement of SERS signals of DOX using the GO loaded with Ag NPs as a SERS-active substrate allows us to monitor the process of the drug release inside the living cell. The SERS results reveal that DOX is initially released from the GO surface inside the lysosomes, then escapes into the cytoplasm, and finally enters the nucleus, while GO, the nanocarrier, remains within the cytoplasm, without entering the nucleus

    Experiments on bright field and dark field high energy electron imaging with thick target material

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    Using a high energy electron beam for the imaging of high density matter with both high spatial-temporal and areal density resolution under extreme states of temperature and pressure is one of the critical challenges in high energy density physics . When a charged particle beam passes through an opaque target, the beam will be scattered with a distribution that depends on the thickness of the material. By collecting the scattered beam either near or off axis, so-called bright field or dark field images can be obtained. Here we report on an electron radiography experiment using 45 MeV electrons from an S-band photo-injector, where scattered electrons, after interacting with a sample, are collected and imaged by a quadrupole imaging system. We achieved a few micrometers (about 4 micrometers) spatial resolution and about 10 micrometers thickness resolution for a silicon target of 300-600 micron thickness. With addition of dark field images that are captured by selecting electrons with large scattering angle, we show that more useful information in determining external details such as outlines, boundaries and defects can be obtained.Comment: 7pages, 7 figure

    Genomewide association study of leprosy.

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    BACKGROUND: The narrow host range of Mycobacterium leprae and the fact that it is refractory to growth in culture has limited research on and the biologic understanding of leprosy. Host genetic factors are thought to influence susceptibility to infection as well as disease progression. METHODS: We performed a two-stage genomewide association study by genotyping 706 patients and 1225 controls using the Human610-Quad BeadChip (Illumina). We then tested three independent replication sets for an association between the presence of leprosy and 93 single-nucleotide polymorphisms (SNPs) that were most strongly associated with the disease in the genomewide association study. Together, these replication sets comprised 3254 patients and 5955 controls. We also carried out tests of heterogeneity of the associations (or lack thereof) between these 93 SNPs and disease, stratified according to clinical subtype (multibacillary vs. paucibacillary). RESULTS: We observed a significant association (P<1.00x10(-10)) between SNPs in the genes CCDC122, C13orf31, NOD2, TNFSF15, HLA-DR, and RIPK2 and a trend toward an association (P=5.10x10(-5)) with a SNP in LRRK2. The associations between the SNPs in C13orf31, LRRK2, NOD2, and RIPK2 and multibacillary leprosy were stronger than the associations between these SNPs and paucibacillary leprosy. CONCLUSIONS: Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae

    Characterization and source identification of fine particulate matter in urban Beijing during the 2015 Spring Festival

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    The Spring Festival (SF) is the most important holiday in China for family reunion and tourism. During the 2015 SF an intensive observation campaign of air quality was conducted to study the impact of the anthropogenic activities and the dynamic characteristics of the sources. During the study period, pollution episodes frequently occurred with 12 days exceeding the Chinese Ambient Air Quality Standards for 24-h average PM2.5 (75 ÎŒg/m3), even 8 days with exceeding 150 ÎŒg/m3. The daily maximum PM2.5 concentration reached 350 ÎŒg/m3 while the hourly minimum visibility was <0.8 km. Three pollution episodes were selected for detailed analysis including chemical characterization and diurnal variation of the PM2.5 and its chemical composition, and sources were identified using the Positive Matrix Factorization model. The first episode occurring before the SF was characterized by more formation of SO42− and NO3− and high crustal enrichment factors for Ag, As, Cd, Cu, Hg, Pb, Se and Zn and seven categories of pollution sources were identified, whereby vehicle emission contributed 38% to the PM2.5. The second episode occurring during the SF was affected heavily by large-scale firework emissions, which led to a significant increase in SO42−, Cl−, OC, K and Ba; these emissions were the largest contributor to the PM2.5 accounting for 36%. During the third episode occurring after the SF, SO42−, NO3−, NH4+ and OC were the major constituents of the PM2.5 and the secondary source was the dominant source with a contribution of 46%. The results provide a detailed understanding on the variation in occurrence, chemical composition and sources of the PM2.5 as well as of the gaseous pollutants affected by the change in anthropogenic activities in Beijing throughout the SF. They highlight the need for limiting the firework emissions during China's most important traditional festival
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